Reaction Details Report a problem with these data
Target
Olfactory receptor class A-like protein 1
Ligand
BDBM50339586
Substrate
n/a
Meas. Tech.
Functional Calcium Imaging Assay
pH
7.4±n/a
EC50
1.9e+3± 3e+2 nM
Comments
extracted
Citation
 Behrens, M; Frank, O; Rawel, H; Ahuja, G; Potting, C; Hofmann, T; Meyerhof, W; Korsching, S ORA1, a zebrafish olfactory receptor ancestral to all mammalian V1R genes, recognizes 4-hydroxyphenylacetic acid, a putative reproductive pheromone. J Biol Chem 289:19778-88 (2014) [PubMed]  Article 
Target
Name:
Olfactory receptor class A-like protein 1
Synonyms:
ORA1_DANRE | Olfactory receptor class A 1 (ORA1) | Vlr2 | ora1
Type:
Protein
Mol. Mass.:
34536.30
Organism:
Danio rerio (Zebrafish)
Description:
Q597G5
Residue:
316
Sequence:
MDLCVTIKGVSFLLQAGLGILANALVLLAYAHIRLAEARLQPVDAILCHLALVDLLLLLTRGVPQTMTVFGMRNLLDDTGCKVVIYTYRIARALSVCITCMLSVFQAVTVAPAAGPLLSGVKARLPQLLAPTFAALWFINMAVCIAAPFFSVAPRNGTVPPFTLNLGFCHVDFHDNLSYVLNGVAVSVRDFAFVGAMLASSGFILLLLHRHRRQVRAVRRSQGSTMETRAARTVLMLVILYSVFFGIDNVIWIYMLTVAQVPPVVADMRVFFSSCYASLSPFLIISSNRKLKARMVCATSEQERQAEDGKNSSGKN
  
Inhibitor
Name:
BDBM50339586
Synonyms:
2-(4-hydroxyphenyl)acetic acid | 4-HYDROXYPHENYLACETATE | 4-Hydroxyphenylacetic acid | CHEMBL1772
Type:
Small organic molecule
Emp. Form.:
C8H8O3
Mol. Mass.:
152.1473
SMILES:
OC(=O)Cc1ccc(O)cc1
Structure:
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