Reaction Details
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Free fatty acid receptor 1
Ligand
BDBM292024
Substrate
n/a
Meas. Tech.
FLIPR Assays
pH
7.4±n/a
Temperature
298.15±n/a K
EC50
306±n/a nM
Comments
extracted
Citation
Chen, H; DeMong, D; Finke, PE; Plummer, CW [5,6]—fused bicyclic antidiabetic compounds US Patent US10100042 Publication Date 10/16/2018 More Info.:
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
31473.32
Organism:
Homo sapiens (Human)
Description:
O14842
Residue:
300
Sequence:
MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
Inhibitor
Name:
BDBM292024
Synonyms:
US10100042, Example 13
Type:
Small organic molecule
Emp. Form.:
C25H21FO3
Mol. Mass.:
388.4308
SMILES:
Cc1cc(F)cc(C)c1-c1cccc(c1)-c1cc2cc(CCC(O)=O)ccc2o1
Structure:
