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Target
Peroxisome proliferator-activated receptor alpha
Ligand
BDBM232292
Substrate
n/a
Meas. Tech.
Kinase Activity Assay
EC50
1175±n/a nM
Citation
 Wang, Y; Zheng, G; Sun, P; Li, Y; Wu, Y; Liu, B; Liu, X; Bai, H; Li, H; Zheng, X Compounds having activating effect on subtypes of peroxisome proliferator-activated receptors and its preparation method and uses US Patent  US9346770 Publication Date 5/24/2016 
Target
Name:
Peroxisome proliferator-activated receptor alpha
Synonyms:
NR1C1 | Nuclear receptor subfamily 1 group C member 1 | PPAR | PPAR alpha/gamma | PPAR-alpha | PPARA | PPARA_HUMAN | Peroxisome Proliferator-Activated Receptor alpha | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor alpha (PPAR alpha)
Type:
Enzyme
Mol. Mass.:
52222.08
Organism:
Homo sapiens (Human)
Description:
Q07869
Residue:
468
Sequence:
MVDTESPLCPLSPLEAGDLESPLSEEFLQEMGNIQEISQSIGEDSSGSFGFTEYQYLGSCPGSDGSVITDTLSPASSPSSVTYPVVPGSVDESPSGALNIECRICGDKASGYHYGVHACEGCKGFFRRTIRLKLVYDKCDRSCKIQKKNRNKCQYCRFHKCLSVGMSHNAIRFGRMPRSEKAKLKAEILTCEHDIEDSETADLKSLAKRIYEAYLKNFNMNKVKARVILSGKASNNPPFVIHDMETLCMAEKTLVAKLVANGIQNKEAEVRIFHCCQCTSVETVTELTEFAKAIPGFANLDLNDQVTLLKYGVYEAIFAMLSSVMNKDGMLVAYGNGFITREFLKSLRKPFCDIMEPKFDFAMKFNALELDDSDISLFVAAIICCGDRPGLLNVGHIEKMQEGIVHVLRLHLQSNHPDDIFLFPKLLQKMADLRQLVTEHAQLVQIIKKTESDAALHPLLQEIYRDMY
  
Inhibitor
Name:
BDBM232292
Synonyms:
US9346770, 5
Type:
Small organic molecule
Emp. Form.:
C24H27NO4
Mol. Mass.:
393.4755
SMILES:
CCc1cc(OCCc2nc(oc2C)-c2ccc(C)cc2)ccc1CCC(O)=O
Structure:
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