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TargetPlatelet-derived growth factor subunit B (PDGFB)
LigandBDBM234587
Substrate/Competitorn/a
Meas. Tech.Kinase Assay
pH7.4±n/a
IC50 55±n/a nM
Commentsextracted
Citation Boral, SMalone, TCWang, S Indole-1-carboxamides as kinase inhibitors US Patent US9353093 Publication Date 5/31/2016
More Info.:Get all data from this article,  Assay Method
 
Platelet-derived growth factor subunit B (PDGFB)
Name:Platelet-derived growth factor subunit B (PDGFB)
Synonyms:PDGF | Platelet-derived growth factor subunit B
Type:Enzyme
Mol. Mass.:27298.80
Organism:Homo sapiens (Human)
Description:P01127
Residue:241
Sequence:
MNRCWALFLSLCCYLRLVSAEGDPIPEELYEMLSDHSIRSFDDLQRLLHGDPGEEDGAEL
DLNMTRSHSGGELESLARGRRSLGSLTIAEPAMIAECKTRTEVFEISRRLIDRTNANFLV
WPPCVEVQRCSGCCNNRNVQCRPTQVQLRPVQVRKIEIVRKKPIFKKATVTLEDHLACKC
ETVAAARPVTRSPGGSQEQRAKTPQTRVTIRTVRVRRPPKGKHRKFKHTHDKTALKETLG
A
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM234587
NameBDBM234587
Synonyms:US9353093, 9
TypeSmall organic molecule
Emp. Form.C23H16F4N4O2
Mol. Mass.456.3924
SMILESNC(=O)n1c(cc2ccccc12)-c1ccc(NC(=O)Nc2cc(ccc2F)C(F)(F)F)cc1
Structure
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