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TargetPlatelet-derived growth factor subunit B (PDGFB)
LigandBDBM234600
Substrate/Competitorn/a
Meas. Tech.Kinase Assay
pH7.4±n/a
IC50 4608±n/a nM
Commentsextracted
Citation Boral, SMalone, TCWang, S Indole-1-carboxamides as kinase inhibitors US Patent US9353093 Publication Date 5/31/2016
More Info.:Get all data from this article,  Assay Method
 
Platelet-derived growth factor subunit B (PDGFB)
Name:Platelet-derived growth factor subunit B (PDGFB)
Synonyms:PDGF | Platelet-derived growth factor subunit B
Type:Enzyme
Mol. Mass.:27298.80
Organism:Homo sapiens (Human)
Description:P01127
Residue:241
Sequence:
MNRCWALFLSLCCYLRLVSAEGDPIPEELYEMLSDHSIRSFDDLQRLLHGDPGEEDGAEL
DLNMTRSHSGGELESLARGRRSLGSLTIAEPAMIAECKTRTEVFEISRRLIDRTNANFLV
WPPCVEVQRCSGCCNNRNVQCRPTQVQLRPVQVRKIEIVRKKPIFKKATVTLEDHLACKC
ETVAAARPVTRSPGGSQEQRAKTPQTRVTIRTVRVRRPPKGKHRKFKHTHDKTALKETLG
A
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM234600
NameBDBM234600
Synonyms:US9353093, 29
TypeSmall organic molecule
Emp. Form.C21H17FN4O2S
Mol. Mass.408.449
SMILESCc1ccc(F)c(NC(=O)Nc2csc(c2)-c2cc3ccccc3n2C(N)=O)c1
Structure
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n/a