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TargetFatty acid-binding protein 4 (FABP4)
LigandBDBM234679
Substrate/Competitorn/a
Meas. Tech.Time Resolved-Fluorescence Energy Transfer (TR-FRET) Assay
pH7.5±n/a
IC50 20±n/a nM
Commentsextracted
Citation Buettelmann, BCeccarelli, SMKuehne, HKuhn, BNeidhart, WObst Sander, URichter, H Non-annulated thiophenylamides US Patent US9353102 Publication Date 5/31/2016
More Info.:Get all data from this article,  Assay Method
 
Fatty acid-binding protein 4 (FABP4)
Name:Fatty acid-binding protein 4 (FABP4)
Synonyms:A-FABP | AFABP | ALBP | Adipocyte lipid-binding protein | Fatty acid binding protein adipocyte | Fatty acid-binding protein 4
Type:Enzyme
Mol. Mass.:14719.23
Organism:Homo sapiens (Human)
Description:P15090
Residue:132
Sequence:
MCDAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPNMIISVNGDVITIKSESTFKN
TEISFILGQEFDEVTADDRKVKSTITLDGGVLVHVQKWDGKSTTIKRKREDDKLVVECVM
KGVTSTRVYERA
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM234679
NameBDBM234679
Synonyms:US9353102, 4.3
TypeSmall organic molecule
Emp. Form.C23H25N3O4S
Mol. Mass.439.527
SMILESCc1sc(NC(=O)C2=C(C3CCC2CC3)C(O)=O)c(-c2nc(no2)C2CC2)c1C1CC1 |t:7,TLB:15:8:10.11:14.13,THB:5:7:10.11:14.13,(-4.55,-2.3,;-3.21,-1.53,;-1.75,-2,;-.84,-.76,;.7,-.76,;1.47,-2.09,;.7,-3.43,;3.01,-2.09,;3.78,-3.43,;5.32,-3.43,;6.09,-2.09,;5.32,-.76,;3.78,-.76,;3.78,-2.01,;5.32,-2.01,;3.01,-4.76,;1.47,-4.76,;3.78,-6.09,;-1.75,.49,;-1.35,1.97,;.11,2.45,;.11,3.99,;-1.35,4.47,;-2.26,3.22,;1.45,4.76,;2.99,4.76,;2.22,6.09,;-3.21,.01,;-4.55,.78,;-5.32,2.11,;-6.09,.78,)|
Structure
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