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TargetFatty acid-binding protein 4 (FABP4)
LigandBDBM234709
Substrate/Competitorn/a
Meas. Tech.Time Resolved-Fluorescence Energy Transfer (TR-FRET) Assay
pH7.5±n/a
IC50 13±n/a nM
Commentsextracted
Citation Buettelmann, BCeccarelli, SMKuehne, HKuhn, BNeidhart, WObst Sander, URichter, H Non-annulated thiophenylamides US Patent US9353102 Publication Date 5/31/2016
More Info.:Get all data from this article,  Assay Method
 
Fatty acid-binding protein 4 (FABP4)
Name:Fatty acid-binding protein 4 (FABP4)
Synonyms:A-FABP | AFABP | ALBP | Adipocyte lipid-binding protein | Fatty acid binding protein adipocyte | Fatty acid-binding protein 4
Type:Enzyme
Mol. Mass.:14719.23
Organism:Homo sapiens (Human)
Description:P15090
Residue:132
Sequence:
MCDAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPNMIISVNGDVITIKSESTFKN
TEISFILGQEFDEVTADDRKVKSTITLDGGVLVHVQKWDGKSTTIKRKREDDKLVVECVM
KGVTSTRVYERA
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM234709
NameBDBM234709
Synonyms:US9353102, 4.15
TypeSmall organic molecule
Emp. Form.C23H25N3O3S2
Mol. Mass.455.593
SMILESCc1c(sc(NC(=O)C2=C(C3CCC2CC3)C(O)=O)c1-c1nc(ns1)C1CC1)C1CC1 |t:8,(-4.49,.69,;-3.16,-.08,;-3.16,-1.62,;-1.7,-2.1,;-.79,-.85,;.75,-.85,;1.52,-2.18,;.75,-3.52,;3.06,-2.18,;4.15,-3.27,;5.64,-2.87,;6.03,-1.39,;4.95,-.3,;3.46,-.7,;4.95,-1.09,;4.15,-2.48,;3.75,-4.76,;2.26,-5.16,;4.84,-5.85,;-1.7,.4,;-.93,1.73,;.54,2.21,;.54,3.75,;-.93,4.22,;-1.83,2.98,;1.87,4.52,;3.41,4.52,;2.64,5.85,;-4.49,-2.39,;-6.03,-2.39,;-5.26,-3.72,)|
Structure
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