Reaction Details Report a problem with these data
Target
Fatty acid-binding protein 5
Ligand
BDBM234682
Substrate
n/a
Meas. Tech.
Time Resolved-Fluorescence Energy Transfer (TR-FRET) Assay
pH
7.5±n/a
IC50
30±n/a nM
Comments
extracted
Citation
 Buettelmann, B; Ceccarelli, SM; Kuehne, H; Kuhn, B; Neidhart, W; Obst Sander, U; Richter, H Non-annulated thiophenylamides US Patent  US9353102 Publication Date 5/31/2016 
Target
Name:
Fatty acid-binding protein 5
Synonyms:
FABP5 | FABP5_HUMAN | Fatty acid binding protein epidermal | Fatty acid-binding protein 5 (FABP5)
Type:
Enzyme
Mol. Mass.:
15164.79
Organism:
Homo sapiens (Human)
Description:
Q01469
Residue:
135
Sequence:
MATVQQLEGRWRLVDSKGFDEYMKELGVGIALRKMGAMAKPDCIITCDGKNLTIKTESTLKTTQFSCTLGEKFEETTADGRKTQTVCNFTDGALVQHQEWDGKESTITRKLKDGKLVVECVMNNVTCTRIYEKVE
  
Inhibitor
Name:
BDBM234682
Synonyms:
US9353102, 5
Type:
Small organic molecule
Emp. Form.:
C18H16F3N3O4S
Mol. Mass.:
427.398
SMILES:
Cc1sc(NC(=O)C2=C(CCC2)C(O)=O)c(-c2nc(no2)C(F)(F)F)c1C1CC1 |t:7|
Structure:
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