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TargetMonoacylglycerol acyltransferase type 2 (h-MGAT2)
LigandBDBM235245
Substrate/Competitorn/a
Meas. Tech.LCMS Assay
IC50 1±n/a nM
Citation Ahmad, SNegash, LA Dihydropyridinone MGAT2 inhibitors US Patent US9365558 Publication Date 6/14/2016
More Info.:Get all data from this article,  Assay Method
 
Monoacylglycerol acyltransferase type 2 (h-MGAT2)
Name:Monoacylglycerol acyltransferase type 2 (h-MGAT2)
Synonyms:Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | Beta-1,2-N-acetylglucosaminyltransferase II | GNT-II | GlcNAc-T II | MGAT2 | Mannoside acetylglucosaminyltransferase 2 | Monoacylglycerol acyltransferase 2 (MGAT2) | N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II | h-MGAT2 (human monoacylglycerol acyltransferase type 2)
Type:n/a
Mol. Mass.:51567.80
Organism:Homo sapiens (Human)
Description:Q10469
Residue:447
Sequence:
MRFRIYKRKVLILTLVVAACGFVLWSSNGRQRKNEALAPPLLDAEPARGAGGRGGDHPSV
AVGIRRVSNVSAASLVPAVPQPEADNLTLRYRSLVYQLNFDQTLRNVDKAGTWAPRELVL
VVQVHNRPEYLRLLLDSLRKAQGIDNVLVIFSHDFWSTEINQLIAGVNFCPVLQVFFPFS
IQLYPNEFPGSDPRDCPRDLPKNAALKLGCINAEYPDSFGHYREAKFSQTKHHWWWKLHF
VWERVKILRDYAGLILFLEEDHYLAPDFYHVFKKMWKLKQQECPECDVLSLGTYSASRSF
YGMADKVDVKTWKSTEHNMGLALTRNAYQKLIECTDTFCTYDDYNWDWTLQYLTVSCLPK
FWKVLVPQIPRIFHAGDCGMHHKKTCRPSTQSAQIESLLNNNKQYMFPETLTISEKFTVV
AISPPRKNGGWGDIRDHELCKSYRRLQ
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  Blast E-value cutoff:
BDBM235245
NameBDBM235245
Synonyms:US9365558, 68
TypeSmall organic molecule
Emp. Form.C29H29F7N2O5S
Mol. Mass.650.605
SMILESCS(=O)(=O)NC(=O)C1=C(C[C@](NC1=O)(c1ccc(OCCCCCC(F)(F)F)cc1F)C(F)(F)F)c1ccc(cc1)C1CC1 |r,t:7|
Structure
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n/a