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Target
Mu-type opioid receptor
Ligand
BDBM236856
Substrate
n/a
Meas. Tech.
[35S]GTPγS Functional Assay
pH
7.4±n/a
Temperature
298.15±n/a K
EC50
>200000±n/a nM
Comments
extracted
Citation
 Kassick, A; Lockman, J; Tafesse, L Substituted morphinans and the use thereof US Patent  US9388162 Publication Date 7/12/2016 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM236856
Synonyms:
US9388162, 62
Type:
Small organic molecule
Emp. Form.:
C26H35NO3
Mol. Mass.:
409.561
SMILES:
COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]4(CC(=O)\C(C[C@@]34O)=C\CC(C)C)c2c1 |r|
Structure:
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