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TargetFructose-1,6-bisphosphate aldolase (FBA)
LigandBDBM237136
Substrate/Competitorn/a
Meas. Tech.Enzymatic Assay
IC50 17000±2100 nM
Kd 6940±970 nM
Citation Pegan, SDAhrendt, KCapodagli, GCCowen, B Antibiotic and anti-parasitic agents that modulate class II fructose 1,6-bisphosphate aldolase US Patent US9394254 Publication Date 7/19/2016
More Info.:Get all data from this article,  Assay Method
 
Fructose-1,6-bisphosphate aldolase (FBA)
Name:Fructose-1,6-bisphosphate aldolase (FBA)
Synonyms:FBP aldolase | FBPA | Fructose-1,6-bisphosphate aldolase | Fructose-bisphosphate aldolase | Probable fructose-bisphosphate aldolase Fba
Type:Protein
Mol. Mass.:36539.01
Organism:Mycobacterium tuberculosis (strain H37Rv)
Description:P9WQA3
Residue:344
Sequence:
MPIATPEVYAEMLGQAKQNSYAFPAINCTSSETVNAAIKGFADAGSDGIIQFSTGGAEFG
SGLGVKDMVTGAVALAEFTHVIAAKYPVNVALHTDHCPKDKLDSYVRPLLAISAQRVSKG
GNPLFQSHMWDGSAVPIDENLAIAQELLKAAAAAKIILEIEIGVVGGEEDGVANEINEKL
YTSPEDFEKTIEALGAGEHGKYLLAATFGNVHGVYKPGNVKLRPDILAQGQQVAAAKLGL
PADAKPFDFVFHGGSGSLKSEIEEALRYGVVKMNVDTDTQYAFTRPIAGHMFTNYDGVLK
VDGEVGVKKVYDPRSYLKKAEASMSQRVVQACNDLHCAGKSLTH
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM237136
NameBDBM237136
Synonyms:US9394254, 5 (HCA)
TypeSmall organic molecule
Emp. Form.C10H7NO3
Mol. Mass.189.1675
SMILESOC(=O)c1ccc2cccc(O)c2n1
Structure
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