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Target
Carbonic anhydrase 6
Ligand
BDBM39340
Substrate
n/a
Meas. Tech.
CA Activity Assay
pH
7.4±n/a
Ki
11670±n/a nM
Comments
extracted
Citation
 Ekinci, D; Kurbanoglu, NI; Salamci, E; Sentürk, M; Supuran, CT Carbonic anhydrase inhibitors: inhibition of human and bovine isoenzymes by benzenesulphonamides, cyclitols and phenolic compounds. J Enzyme Inhib Med Chem 27:845-8 (2012) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 6
Synonyms:
CA-VI | CA6 | CAH6_HUMAN | Carbonate dehydratase VI | Carbonic Anhydrase VI | Carbonic anhydrase | Carbonic anhydrase 6 | Carbonic anhydrase 6 (CA VI) | Carbonic anhydrase 6 (CA-VI) | Carbonic anhydrase VI (CA VI) | Salivary carbonic anhydrase | Secreted carbonic anhydrase
Type:
Enzyme
Mol. Mass.:
35371.40
Organism:
Homo sapiens (Human)
Description:
P23280
Residue:
308
Sequence:
MRALVLLLSLFLLGGQAQHVSDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNKTIHNDYRRTQPLNHRVVESNFPNQEYTLGSEFQFYLHKIEEILDYLRRALN
  
Inhibitor
Name:
BDBM39340
Synonyms:
4-Amino-N-(pyrimidin-2-yl) benzenesulfonamide (Sulfadiazine) (14) | MLS000069725 | SMR000058213 | SULFAPYRIDINE | cid_5336
Type:
Small organic molecule
Emp. Form.:
C11H11N3O2S
Mol. Mass.:
249.289
SMILES:
Nc1ccc(cc1)S(=O)(=O)Nc1ccccn1
Structure:
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