Reaction Details Report a problem with these data
Target
Carbonic anhydrase 3
Ligand
BDBM26188
Substrate
n/a
Meas. Tech.
Esterase Activity Assay
pH
7.4±n/a
Ki
5.79e+3±n/a nM
Comments
extracted
Citation
 Koz, ÿ; Ekinci, D; Perrone, A; Piacente, S; Alankus-Çaliskan, ÿ; Bedir, E; Supuran, CT Analysis of saponins and phenolic compounds as inhibitors of a-carbonic anhydrase isoenzymes. J Enzyme Inhib Med Chem 28:412-7 (2013) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 3
Synonyms:
CA-III | CA3 | CAH3_BOVIN | Carbonate dehydratase III | Carbonic anhydrase 3 | Carbonic anhydrase 3 (CA III) | Carbonic anhydrase III
Type:
Enzyme
Mol. Mass.:
29376.92
Organism:
Bos taurus (Cattle)
Description:
Q3SZX4
Residue:
260
Sequence:
MAKEWGYADHNGPDHWHELFPNAKGENQSPIELNTKEISHDPSLKPWTASYDPGSAKTILNNGKTCRVVFDDTYDRSMLRGGPLAAPYRLRQFHLHWGSSDDHGSEHSVDGVKYAAELHLVHWNSKYNSYATALKHADGIAVVGVFLKIGREKGEFQLLLDALDKIKTKGKEAPFNNFNPSCLFPACRDYWTYHGSFTTPPCEECIVWLLLKEPITVSSDQIAKLRTLYSSAENEPPVPLVRNWRPPQPIKGRIVKASFK
  
Inhibitor
Name:
BDBM26188
Synonyms:
α-CA inhibitor, 12 | 1,2-Dihydroxybenzene, XI | 1,2-dihydroxybenzene | CHEMBL280998 | benzene-1,2-diol | phenol derivative, 2
Type:
Small organic molecule
Emp. Form.:
C6H6O2
Mol. Mass.:
110.1106
SMILES:
Oc1ccccc1O
Structure:
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