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Target
Cannabinoid receptor 2
Ligand
BDBM240380
Substrate
n/a
Meas. Tech.
cAMP Assay
Temperature
310.15±n/a K
EC50
55.4±n/a nM
Comments
extracted
Citation
 Grether, U; Kimbara, A; Nettekoven, M; Ricklin, F; Roever, S; Rogers-Evans, M; Rombach, D; Schulz-Gasch, T; Westphal, M Pyridine-2-amides useful as CB2 agonists US Patent  US9409866 Publication Date 8/9/2016 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM240380
Synonyms:
US9409866, 95
Type:
Small organic molecule
Emp. Form.:
C18H20F5N5O5S
Mol. Mass.:
513.439
SMILES:
Cc1nc(no1)C(C)(CS(C)(=O)=O)NC(=O)c1cc(OCC(F)(F)F)c(cn1)N1CC(F)(F)C1
Structure:
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