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TargetXIAP protein BIR2
LigandBDBM240881
Substrate/Competitorn/a
Meas. Tech.TR-FRET Assay
pH7.5±n/a
Temperature298.15±n/a K
IC50 1.25±n/a nM
Commentsextracted
Citation Mischke, SG Dimeric compounds US Patent US9409888 Publication Date 8/9/2016
More Info.:Get all data from this article,  Assay Method
 
XIAP protein BIR2
Name:XIAP protein BIR2
Synonyms:Baculoviral IAP repeat-containing protein 2 (BIR2) | E3 ubiquitin-protein ligase XIAP (BIR2) | E3 ubiquitin-protein ligase XIAP BIR2
Type:Protein
Mol. Mass.:14676.71
Organism:Artificial Sequence
Description:TR-FRET peptide Corresponds to amino acids 124-240 of human XIAP.
Residue:125
Sequence:
MRHHHHHHRDHFALDRPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPD
YAHLTPRELASAGLYYTGIGDQVQCFACGGKLKNWEPGDRAWSEHRRHFPNCFFVLGRNL
NIRSE
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM240881
NameBDBM240881
Synonyms:US9409888, 1
TypeSmall organic molecule
Emp. Form.C57H66BrN9O8
Mol. Mass.1085.093
SMILESCN[C@@H](C)C(=O)N[C@@H](C1CCCCC1)C(=O)N1C[C@@H](C[C@@H]1C(=O)NCc1ccccc1)NC(=O)c1ccc(cc1)C(=O)N1C[C@H](NC(=O)[C@@H](C)NC)C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccccc12
Structure
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