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TargetXIAP protein BIR2
LigandBDBM240894
Substrate/Competitorn/a
Meas. Tech.TR-FRET Assay
pH7.5±n/a
Temperature298.15±n/a K
IC50 1.43±n/a nM
Commentsextracted
Citation Mischke, SG Dimeric compounds US Patent US9409888 Publication Date 8/9/2016
More Info.:Get all data from this article,  Assay Method
 
XIAP protein BIR2
Name:XIAP protein BIR2
Synonyms:Baculoviral IAP repeat-containing protein 2 (BIR2) | E3 ubiquitin-protein ligase XIAP (BIR2) | E3 ubiquitin-protein ligase XIAP BIR2
Type:Protein
Mol. Mass.:14676.71
Organism:Artificial Sequence
Description:TR-FRET peptide Corresponds to amino acids 124-240 of human XIAP.
Residue:125
Sequence:
MRHHHHHHRDHFALDRPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPD
YAHLTPRELASAGLYYTGIGDQVQCFACGGKLKNWEPGDRAWSEHRRHFPNCFFVLGRNL
NIRSE
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM240894
NameBDBM240894
Synonyms:US9409888, 14
TypeSmall organic molecule
Emp. Form.C53H54Br2N8O8
Mol. Mass.1090.853
SMILESCN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CC(=O)N2C[C@H](NC(=O)[C@H](C)NC)C(=O)N(Cc3c(OC)ccc4cc(Br)ccc34)c3ccccc23)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O
Structure
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