Reaction Details
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Superoxide dismutase [Cu-Zn]
Ligand
BDBM241955
Substrate
n/a
Meas. Tech.
SOD Assay (Kinetic Analysis)
Ki
1.172e+4±n/a nM
Citation
Oyatsi, F; Whiteley, CG Interaction of superoxide dismutase with the glycine zipper regions of ß-amyloid peptides: is there an implication towards Alzheimer's disease and oxidative stress? J Enzyme Inhib Med Chem 28:727-33 (2013) [PubMed] Article More Info.:
Target
Name:
Superoxide dismutase [Cu-Zn]
Synonyms:
SOD1 | SODC_BOVIN | Superoxide dismutase (SOD)
Type:
Enzyme
Mol. Mass.:
15681.34
Organism:
Bos taurus (Cattle)
Description:
P00442
Residue:
152
Sequence:
MATKAVCVLKGDGPVQGTIHFEAKGDTVVVTGSITGLTEGDHGFHVHQFGDNTQGCTSAGPHFNPLSKKHGGPKDEERHVGDLGNVTADKNGVAIVDIVDPLISLSGEYSIIGRTMVVHEKPDDLGRGGNEESTKTGNAGSRLACGVIGIAK
Inhibitor
Name:
BDBM241955
Synonyms:
Aβ (1-40) | DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV
Type:
Small organic molecule
Emp. Form.:
C194H295N53O58S
Mol. Mass.:
4329.803
SMILES:
CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CC(O)=O)C(C)C)C(C)C)C(C)C)[C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(O)=O |r|
Structure:
