Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM242507
Substrate
n/a
Meas. Tech.
Binding Assay
Temperature
303.15±n/a K
Ki
266±n/a nM
IC50
471±n/a nM
Comments
extracted
Citation
 Yacovan, A; Alroy, I; Aizikovich, A; Mirilashvili, S; Grynszpan, F Sulfonamide derivatives with therapeutic indications US Patent  US9422235 Publication Date 8/23/2016 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM242507
Synonyms:
US9422235, 90
Type:
Small organic molecule
Emp. Form.:
C18H25F3N2O2S
Mol. Mass.:
390.464
SMILES:
CC1CCC(CC1)Nc1ccc(c(c1)C(F)(F)F)S(=O)(=O)NCC1CC1 |(-4.76,1.25,;-3.99,-.09,;-4.76,-1.42,;-3.99,-2.75,;-2.45,-2.75,;-1.68,-1.42,;-2.45,-.09,;-1.68,-4.09,;-.14,-4.09,;.63,-5.42,;2.17,-5.42,;2.94,-4.09,;2.17,-2.75,;.63,-2.75,;2.94,-1.42,;3.71,-.09,;1.6,-.65,;4.44,-1.74,;4.48,-4.09,;6.02,-4.09,;4.48,-2.55,;4.48,-5.63,;3.14,-6.4,;3.14,-7.94,;3.91,-9.27,;2.37,-9.27,)|
Structure:
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