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TargetXIAP protein BIR2
LigandBDBM242836
Substrate/Competitorn/a
Meas. Tech.TR-FRET Assay
pH7.5±n/a
Temperature310.15±n/a K
IC50 5±n/a nM
Commentsextracted
Citation Hogg, JHLe, KLou, YMischke, SGRemiszewski, S Azaheterocycles as BIR2 and/or BIR3 inhibitors US Patent US9422332 Publication Date 8/23/2016
More Info.:Get all data from this article,  Assay Method
 
XIAP protein BIR2
Name:XIAP protein BIR2
Synonyms:Baculoviral IAP repeat-containing protein 2 (BIR2) | E3 ubiquitin-protein ligase XIAP (BIR2) | E3 ubiquitin-protein ligase XIAP BIR2
Type:Protein
Mol. Mass.:14676.71
Organism:Artificial Sequence
Description:TR-FRET peptide Corresponds to amino acids 124-240 of human XIAP.
Residue:125
Sequence:
MRHHHHHHRDHFALDRPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPD
YAHLTPRELASAGLYYTGIGDQVQCFACGGKLKNWEPGDRAWSEHRRHFPNCFFVLGRNL
NIRSE
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BDBM242836
NameBDBM242836
Synonyms:US9422332, 21
TypeSmall organic molecule
Emp. Form.C28H32N4O3
Mol. Mass.472.5787
SMILESCN[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N1Cc2ccccc2[C@H]1C(=O)Nc1cccc2ccccc12 |r|
Structure
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