Reaction Details Report a problem with these data
Target
Secreted chorismate mutase
Ligand
BDBM248170
Substrate
n/a
Meas. Tech.
CM Assay
pH
7.5±0
Temperature
310.15±0 K
IC50
2.158e+4± 3.0e+3 nM
Citation
 Alokam, R; Jeankumar, VU; Sridevi, JP; Matikonda, SS; Peddi, S; Alvala, M; Yogeeswari, P; Sriram, D Identification and structure-activity relationship study of carvacrol derivatives as Mycobacterium tuberculosis chorismate mutase inhibitors. J Enzyme Inhib Med Chem 29:547-54 (2014) [PubMed]  Article 
Target
Name:
Secreted chorismate mutase
Synonyms:
Chorismate mutase (CM) | Chorismate mutase (MTB CM) | Chorismate mutase-related protein | SCMU_MYCTU
Type:
Protein
Mol. Mass.:
21942.03
Organism:
Mycobacterium tuberculosis H37Rv
Description:
n/a
Residue:
199
Sequence:
MLTRPREIYLATAVSIGILLSLIAPLGPPLARADGTSQLAELVDAAAERLEVADPVAAFKWRAQLPIEDSGRVEQQLAKLGEDARSQHIDPDYVTRVFDDQIRATEAIEYSRFSDWKLNPASAPPEPPDLSASRSAIDSLNNRMLSQIWSHWSLLSAPSCAAQLDRAKRDIVRSRHLDSLYQRALTTATQSYCQALPPA
  
Inhibitor
Name:
BDBM248170
Synonyms:
Thymol derivative, 21
Type:
Small organic molecule
Emp. Form.:
C11H16O
Mol. Mass.:
164.2441
SMILES:
COc1cc(C)ccc1C(C)C
Structure:
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