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Target
Retinol-binding protein 4
Ligand
BDBM249466
Substrate
n/a
Meas. Tech.
Scintillation Proximity Binding Assay
pH
7.4±n/a
Temperature
277.15±n/a K
IC50
5.731617±n/a nM
Comments
extracted
Citation
 Petrukhin, K; Cioffi, C; Johnson, G; Allikmets, R; Freeman, E; Chen, P; Conlon, M; Zhu, L Substituted 4-phenylpiperidines, their preparation and use US Patent  US9434727 Publication Date 9/6/2016 
Target
Name:
Retinol-binding protein 4
Synonyms:
PRBP | Plasma retinol-binding protein | RBP | RBP4 | RET4_HUMAN | Retinol-binding protein 4 | Retinol-binding protein 4 (RBP4) | spa binding assay for rbp4
Type:
Protein
Mol. Mass.:
23008.75
Organism:
Homo sapiens (Human)
Description:
P02753
Residue:
201
Sequence:
MKWVWALLLLAALGSGRAERDCRVSSFRVKENFDKARFSGTWYAMAKKDPEGLFLQDNIVAEFSVDETGQMSATAKGRVRLLNNWDVCADMVGTFTDTEDPAKFKMKYWGVASFLQKGNDDHWIVDTDYDTYAVQYSCRLLNLDGTCADSYSFVFSRDPNGLPPEAQKIVRQRQEELCLARQYRLIVHNGYCDGRSERNLL
  
Inhibitor
Name:
BDBM249466
Synonyms:
US10072016, Compound 65 | US10407433, Compound 65 | US10913746, Compound 65 | US11649240, Compound 65 | US9434727, 65 | US9777010, Compound 65
Type:
Small organic molecule
Emp. Form.:
C20H15F4N5O
Mol. Mass.:
417.3596
SMILES:
Fc1cccc(C2CCN(CC2)C(=O)c2nnc3ccc(cn23)C#N)c1C(F)(F)F
Structure:
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