Reaction Details Report a problem with these data
Target
C-X-C motif chemokine 10
Ligand
BDBM249719
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
Temperature
298.15±n/a K
IC50
46±n/a nM
Comments
extracted
Citation
 Bata, I; Bartane Bodor, V; Vasas, A; Buzder-Lantos, P; Ferenczy, G; Tomoskozi, Z; Szeleczky, G; Szamosvolgyi, Z Substituted B-amino acid derivatives as CXCR3 receptor antagonists US Patent  US9447038 Publication Date 9/20/2016 
Target
Name:
C-X-C motif chemokine 10
Synonyms:
C-X-C motif chemokine 10 (CXCL10) | CXCL10 | CXL10_HUMAN | INP10 | SCYB10
Type:
Enzyme
Mol. Mass.:
10892.04
Organism:
Homo sapiens (Human)
Description:
P02778
Residue:
98
Sequence:
MNQTAILICCLIFLTLSGIQGVPLSRTVRCTCISISNQPVNPRSLEKLEIIPASQFCPRVEIIATMKKKGEKRCLNPESKAIKNLLKAVSKERSKRSP
  
Inhibitor
Name:
BDBM249719
Synonyms:
US9447038, 147
Type:
Small organic molecule
Emp. Form.:
C31H38N2O6
Mol. Mass.:
534.6432
SMILES:
Cc1cc(CN(CC2CCCC2)C(CC(O)=O)c2ccc3OCCc3c2)ccc1OCCN1C(=O)CCC1=O
Structure:
Search PDB for entries with ligand similarity: