Reaction Details Report a problem with these data
Target
Lysophosphatidic acid receptor 5
Ligand
BDBM251743
Substrate
n/a
Meas. Tech.
Receptor Assay
Temperature
310.15±n/a K
IC50
68±n/a nM
Comments
extracted
Citation
 Buffham, W; Canning, H; Davenport, R; Farnaby, W; Mack, S; Parmar, A; Wright, S Compounds US Patent  US9464060 Publication Date 10/11/2016 
Target
Name:
Lysophosphatidic acid receptor 5
Synonyms:
GPR92 | GPR93 | LPAR5 | LPAR5_HUMAN | Lysophosphatidic acid receptor 5 | Lysophosphatidic acid receptor 5 (LPA5)
Type:
Enzyme
Mol. Mass.:
41372.36
Organism:
Homo sapiens (Human)
Description:
Q9H1C0
Residue:
372
Sequence:
MLANSSSTNSSVLPCPDYRPTHRLHLVVYSLVLAAGLPLNALALWVFLRALRVHSVVSVYMCNLAASDLLFTLSLPVRLSYYALHHWPFPDLLCQTTGAIFQMNMYGSCIFLMLINVDRYAAIVHPLRLRHLRRPRVARLLCLGVWALILVFAVPAARVHRPSRCRYRDLEVRLCFESFSDELWKGRLLPLVLLAEALGFLLPLAAVVYSSGRVFWTLARPDATQSQRRRKTVRLLLANLVIFLLCFVPYNSTLAVYGLLRSKLVAASVPARDRVRGVLMVMVLLAGANCVLDPLVYYFSAEGFRNTLRGLGTPHRARTSATNGTRAALAQSERSAVTTDATRPDAASQGLLRPSDSHSLSSFTQCPQDSAL
  
Inhibitor
Name:
BDBM251743
Synonyms:
US10100018, Example 79 | US9464060, 79
Type:
Small organic molecule
Emp. Form.:
C26H24FNO5
Mol. Mass.:
449.4709
SMILES:
COc1ccc(F)cc1Oc1ccc(cc1)C(=O)N(CC1CC1)Cc1ccc(cc1)C(O)=O
Structure:
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