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TargetMelanocortin receptor 4
LigandBDBM135752
Substrate/Competitorn/a
Meas. Tech.Competitive Inhibition Assay Using [I125]-NDP-a-MSH
pH7.5±n/a
Temperature310.15±n/a K
Ki 0.4±n/a nM
Commentsextracted
Citation Shi, YSharma, SDDodd, JHYang, W Melanocortin receptor-specific heptapeptides US Patent US9458201 Publication Date 10/4/2016
More Info.:Get all data from this article,  Assay Method
 
Melanocortin receptor 4
Name:Melanocortin receptor 4
Synonyms:MC4-R | MC4R | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:Enzyme
Mol. Mass.:36949.50
Organism:Homo sapiens (Human)
Description:P32245
Residue:332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLL
ENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVN
IDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVS
GILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGAN
MKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPL
IYALRSQELRKTFKEIICCYPLGGLCDLSSRY
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM135752
NameBDBM135752
Synonyms:US10179804, Example 137 | US8846601, 137 | US9458201, 137
TypeSmall organic molecule
Emp. Form.C53H79N17O9
Mol. Mass.1098.3029
SMILESNCC[C@@H]1NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC1=O)C(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)C1CCCCC1 |r|
Structure
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