Reaction Details
Report a problem with these data
Report a problem with these dataTarget
D-amino-acid oxidase
Ligand
BDBM50117810
Substrate
n/a
Meas. Tech.
In Vitro Assay
pH
8.5±n/a
Temperature
298.15±n/a K
IC50
900±n/a nM
Comments
extracted
Citation
Tsukamoto, T; Slusher, BS; Ferraris, DV; Rojas, C; Hin, N; Duvall, B Inhibitors of D-amino acid oxidase US Patent US9505753 Publication Date 11/29/2016 More Info.:
Target
Name:
D-amino-acid oxidase
Synonyms:
D-amino-acid oxidase (DAAO) | DAAO | DAMOX | DAO | OXDA_HUMAN
Type:
Homodimer
Mol. Mass.:
39476.06
Organism:
Homo sapiens (Human)
Description:
P14920
Residue:
347
Sequence:
MRVVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLTTTDVAAGLWQPYLSDPNNPQEADWSQQTFDYLLSHVHSPNAENLGLFLISGYNLFHEAIPDPSWKDTVLGFRKLTPRELDMFPDYGYGWFHTSLILEGKNYLQWLTERLTERGVKFFQRKVESFEEVAREGADVIVNCTGVWAGALQRDPLLQPGRGQIMKVDAPWMKHFILTHDPERGIYNSPYIIPGTQTVTLGGIFQLGNWSELNNIQDHNTIWEGCCRLEPTLKNARIIGERTGFRPVRPQIRLEREQLRTGPSNTEVIHNYGHGGYGLTIHWGCALEAAKLFGRILEEKKLSRMPPSHL
Inhibitor
Name:
BDBM50117810
Synonyms:
CHEMBL3613923 | US9505753, 10l
Type:
Small organic molecule
Emp. Form.:
C10H10N4O3
Mol. Mass.:
234.2114
SMILES:
Oc1nn(CCc2ccccn2)c(=O)[nH]c1=O
Structure:
