Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM259684
Substrate
n/a
Meas. Tech.
cAMP Assay
Temperature
310.15±n/a K
EC50
229.4±n/a nM
Comments
extracted
Citation
 Bendels, S; Grether, U; Kimbara, A; Nettekoven, M; Roever, S; Rogers-Evans, M; Schulz-Gasch, T Purine derivatives as CB2 receptor agonists US Patent  US9505762 Publication Date 11/29/2016 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM259684
Synonyms:
US9505762, 52
Type:
Small organic molecule
Emp. Form.:
C23H30N6O3S
Mol. Mass.:
470.588
SMILES:
CC(=O)N[C@H]1CCN(C1)c1nc(nc2n(Cc3ccccc3S(C)(=O)=O)cnc12)C(C)(C)C |r|
Structure:
Search PDB for entries with ligand similarity: