Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM260001
Substrate
n/a
Meas. Tech.
cAMP Assay
Temperature
310.15±n/a K
EC50
17.2±n/a nM
Comments
extracted
Citation
 Grether, U; Kimbara, A; Matthias, N; Fabienne, R; Stephan, R; Rogers-Evans, M; Schulz-Gasch, T Pyrazole compounds as CB2 agonists US Patent  US9512132 Publication Date 12/6/2016 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM260001
Synonyms:
US9512132, 37
Type:
Small organic molecule
Emp. Form.:
C17H13ClF5N5
Mol. Mass.:
417.764
SMILES:
FC(F)(F)c1ccccc1Cn1ncc2c(nc(Cl)nc12)N1CCC(F)(F)C1
Structure:
Search PDB for entries with ligand similarity: