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Target
Cannabinoid receptor 2
Ligand
BDBM260006
Substrate
n/a
Meas. Tech.
cAMP Assay
Temperature
310.15±n/a K
EC50
4.3±n/a nM
Comments
extracted
Citation
 Dhurwasulu, B; Grether, U; Nettekoven, M; Roever, S; Rogers-Evans, M; Schulz-Gasch, T Pyrazine derivatives as CB2 receptor agonists US Patent  US9512141 Publication Date 12/6/2016 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM260006
Synonyms:
US9512141, 4
Type:
Small organic molecule
Emp. Form.:
C18H24F2N4O3
Mol. Mass.:
382.405
SMILES:
CC1(C)COCCN1C(=O)c1cnc(N2CC(F)(F)C2)c(OCC2CC2)n1
Structure:
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