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Target
D-amino-acid oxidase
Ligand
BDBM406218
Substrate
n/a
Meas. Tech.
In Vitro Measurements of porcine D-Amino Acid Oxidase (DAAO) Activities
IC50
30000000±n/a nM
Citation
 Tsai, GE; Wang, C; Hsieh, Y D-amino acid oxidase inhibitors and therapeutic uses thereof US Patent  US10336724 Publication Date 7/2/2019 
Target
Name:
D-amino-acid oxidase
Synonyms:
D-Amino Acid Oxidase (DAAO) | D-amino-acid oxidase (DAAO) | DAMOX | DAO | OXDA_PIG
Type:
Flavoprotein
Mol. Mass.:
39338.01
Organism:
Sus scrofa (pig)
Description:
Homodimer.
Residue:
347
Sequence:
MRVVVIGAGVIGLSTALCIHERYHSVLQPLDVKVYADRFTPFTTTDVAAGLWQPYTSEPSNPQEANWNQQTFNYLLSHIGSPNAANMGLTPVSGYNLFREAVPDPYWKDMVLGFRKLTPRELDMFPDYRYGWFNTSLILEGRKYLQWLTERLTERGVKFFLRKVESFEEVARGGADVIINCTGVWAGVLQPDPLLQPGRGQIIKVDAPWLKNFIITHDLERGIYNSPYIIPGLQAVTLGGTFQVGNWNEINNIQDHNTIWEGCCRLEPTLKDAKIVGEYTGFRPVRPQVRLEREQLRFGSSNTEVIHNYGHGGYGLTIHWGCALEVAKLFGKVLEERNLLTMPPSHL
  
Inhibitor
Name:
BDBM406218
Synonyms:
6-(hydroxymethyl)-4-oxo-4H-pyran-3-yl 1H-pyrrole-2-carboxylate | US10336724, Compound 1
Type:
Small organic molecule
Emp. Form.:
C11H9NO5
Mol. Mass.:
235.1929
SMILES:
OCc1cc(=O)c(OC(=O)c2ccc[nH]2)co1
Structure:
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