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Target
Leukotriene B4 receptor 1
Ligand
BDBM406388
Substrate
n/a
Meas. Tech.
BLT-1 cAMP Assay
EC50
9.00±n/a nM
Citation
 Han, Y; Lim, J; Tummanapalli, S; Siliphaivanh, P; Spencer, K Aryl acylsulfonamides as BLT1 antagonists US Patent  US10336733 Publication Date 7/2/2019 
Target
Name:
Leukotriene B4 receptor 1
Synonyms:
BLT | BLT1 | BLTR | CMKRL1 | Chemoattractant receptor-like 1 | G-protein coupled receptor 16 | GPR16 | LT4R1_HUMAN | LTB4-R 1 | LTB4R | Leukotriene B4 R1 | Leukotriene B4 receptor | Leukotriene B4 receptor 1 | P2RY7 | P2Y purinoceptor 7 | P2Y7
Type:
Enzyme Catalytic Domain
Mol. Mass.:
37582.68
Organism:
Homo sapiens (Human)
Description:
Q15722
Residue:
352
Sequence:
MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNLALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVARPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAFHLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVVNLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGFVAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN
  
Inhibitor
Name:
BDBM406388
Synonyms:
N-(tert-Butylsulfonyl)-2-((rac-trans)-4-hydroxy-3-(thiazol-4-ylmethyl)chroman-7-yl)benzamide | US10336733, Example 32 | US10336733, Example 34
Type:
Small organic molecule
Emp. Form.:
C24H26N2O5S2
Mol. Mass.:
486.604
SMILES:
CC(C)(C)S(=O)(=O)NC(=O)c1ccccc1-c1ccc2[C@H](O)[C@@H](Cc3cscn3)COc2c1 |r|
Structure:
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