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Target
Free fatty acid receptor 2
Ligand
BDBM403945
Substrate
n/a
Meas. Tech.
GTPγS Assay
EC50
<200±n/a nM
Citation
 Hoveyda, HR; Schils, D; Zoute, L; Parcq, J Substituted pyrrolidines as G-protein coupled receptor 43 agonists US Patent  US10358416 Publication Date 7/23/2019 
Target
Name:
Free fatty acid receptor 2
Synonyms:
FFA2 | FFAR2 | FFAR2_HUMAN | G-protein coupled receptor 43 | GPCR43 | GPR43
Type:
PROTEIN
Mol. Mass.:
37156.44
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1508993
Residue:
330
Sequence:
MLPDWKSSLILMAYIIIFLTGLPANLLALRAFVGRIRQPQPAPVHILLLSLTLADLLLLLLLPFKIIEAASNFRWYLPKVVCALTSFGFYSSIYCSTWLLAGISIERYLGVAFPVQYKLSRRPLYGVIAALVAWVMSFGHCTIVIIVQYLNTTEQVRSGNEITCYENFTDNQLDVVLPVRLELCLVLFFIPMAVTIFCYWRFVWIMLSQPLVGAQRRRRAVGLAVVTLLNFLVCFGPYNVSHLVGYHQRKSPWWRSIAVVFSSLNASLDPLLFYFSSSVVRRAFGRGLQVLRNQGSSLLGRRGKDTAEGTNEDRGVGQGEGMPSSDFTTE
  
Inhibitor
Name:
BDBM403945
Synonyms:
(2S,5R)-1-(2-chloro-[1,1'-biphenyl]-4-carbonyl)-5-(2-chlorophenyl)pyrrolidine-2-carboxylic acid | US10017468, Compound 224 | US10781171, Compound 224 | US11072582, Compound 224
Type:
Small organic molecule
Emp. Form.:
C24H19Cl2NO3
Mol. Mass.:
440.319
SMILES:
OC(=O)[C@@H]1CC[C@@H](N1C(=O)c1ccc(c(Cl)c1)-c1ccccc1)c1ccccc1Cl
Structure:
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