Reaction Details Report a problem with these data
Target
Epoxide hydrolase 1
Ligand
BDBM25737
Substrate
n/a
Meas. Tech.
Inhibition Assay
IC50
3.00±n/a nM
Citation
 Guedes, AG; Hammock, BD; Morisseau, C Treatment of inflammatory disorders in non-human mammals US Patent  US10383835 Publication Date 8/20/2019 
Target
Name:
Epoxide hydrolase 1
Synonyms:
EPHX1
Type:
n/a
Mol. Mass.:
55532.32
Organism:
Felis catus (Cat) (Felis silvestris catus)
Description:
A0A2I2V3F9
Residue:
483
Sequence:
MLTSPSFSLGVTATMVPTVPSTCPRLLKGKGIMWLEILLASVLAFVVYWFVSRDKEETLPLEDGWWGPGARPTAPEDESIRPFKVETSDEEIKDLHRRIDGTRLTPPLEDSRFHYGFNSNYLKKILSYWRNEFDWRKQVEMLNRYPHFKTRIEGLDIHFVHVKPPQLPPGRTPKPLLMVHGWPGSFYEFYKIIPLLTDPANHGLSEEHVFEVICPSIPGYAFSEAASKKGLNSVATARIFYKLMLRLGFREFYIQGGDWGALICTHMAQMVPSHVKGLHLNMAFILNGRILTLFLVRHCPRLFGFTQRDMELMLPFKEKIFYKPLRESGYMHIQSTKPDTVGCALNDSPAGLAAYILEKFSTWTDSEFQELEDGGLERKFSLDDLLTNVMLYWTTGTITSSQRFYKENRGQLFKQDRVKVSVPTGLAAFPCELMHIPERWVKGKYPRLVSYSYMPRGGHFAALEEPELLARDIRKFVGLLELP
  
Inhibitor
Name:
BDBM25737
Synonyms:
12-[(adamantan-1-ylcarbamoyl)amino]dodecanoic acid | CHEMBL215387 | US10383835, Compound 700 | Urea-based compound, 18
Type:
Small organic molecule
Emp. Form.:
C23H40N2O3
Mol. Mass.:
392.5753
SMILES:
OC(=O)CCCCCCCCCCCNC(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:25:20:27:24.23.26,25:24:20.21.19:27,THB:23:22:19:24.25.26,23:24:19:22.21.27|
Structure:
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