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Target
Uracil-DNA glycosylase
Ligand
BDBM294517
Substrate
n/a
Meas. Tech.
Processive DNA synthesis assay
pH
7.5±n/a
EC50
13300±n/a nM
Comments
extracted
Citation
 Ricciardi, RP; Reitz, AB; Parker, MH; Baugh, SD; Nuth, M; Guan, H Antivirals against molluscum contagiosum virus US Patent  US10112895 Publication Date 10/30/2018 
Target
Name:
Uracil-DNA glycosylase
Synonyms:
OPG116 | UDG | UNG | UNG_VACCW
Type:
PROTEIN
Mol. Mass.:
25071.48
Organism:
Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strainWR))
Description:
ChEMBL_747132
Residue:
218
Sequence:
MNSVTVSHAPYTITYHDDWEPVMSQLVEFYNEVASWLLRDETSPIPDKFFIQLKQPLRNKRVCVCGIDPYPKDGTGVPFESPNFTKKSIKEIASSISRLTGVIDYKGYNLNIIDGVIPWNYYLSCKLGETKSHAIYWDKISKLLLQHITKHVSVLYCLGKTDYSNIRAKLESPVTTIVGYHPAARDRQFEKDRSFEIINVLLELDNKAPINWAQGFIY
  
Inhibitor
Name:
BDBM294517
Synonyms:
4-[[2-[(3- nitrophenyl)methoxy]phenyl] methylamino]phenol | US10112895, Compound 9
Type:
Small organic molecule
Emp. Form.:
C20H18N2O4
Mol. Mass.:
350.3679
SMILES:
Oc1ccc(NCc2ccccc2OCc2cccc(c2)[N+]([O-])=O)cc1
Structure:
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