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Target
Uracil-DNA glycosylase
Ligand
BDBM33154
Substrate
n/a
Meas. Tech.
Processive DNA synthesis assay
pH
7.5±n/a
EC50
35600±n/a nM
Comments
extracted
Citation
 Ricciardi, RP; Reitz, AB; Parker, MH; Baugh, SD; Nuth, M; Guan, H Antivirals against molluscum contagiosum virus US Patent  US10112895 Publication Date 10/30/2018 
Target
Name:
Uracil-DNA glycosylase
Synonyms:
OPG116 | UDG | UNG | UNG_VACCW
Type:
PROTEIN
Mol. Mass.:
25071.48
Organism:
Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strainWR))
Description:
ChEMBL_747132
Residue:
218
Sequence:
MNSVTVSHAPYTITYHDDWEPVMSQLVEFYNEVASWLLRDETSPIPDKFFIQLKQPLRNKRVCVCGIDPYPKDGTGVPFESPNFTKKSIKEIASSISRLTGVIDYKGYNLNIIDGVIPWNYYLSCKLGETKSHAIYWDKISKLLLQHITKHVSVLYCLGKTDYSNIRAKLESPVTTIVGYHPAARDRQFEKDRSFEIINVLLELDNKAPINWAQGFIY
  
Inhibitor
Name:
BDBM33154
Synonyms:
4-[(2-benzoxybenzyl)amino]phenol | 4-[(2-phenylmethoxyphenyl)methylamino]phenol | 4-{[2-(benzyloxy)benzyl]amino}phenol | MLS000704391 | SMR000231540 | US10112895, Compound 10 | cid_833990
Type:
Small organic molecule
Emp. Form.:
C20H19NO2
Mol. Mass.:
305.3704
SMILES:
Oc1ccc(NCc2ccccc2OCc2ccccc2)cc1
Structure:
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