Target
Uracil-DNA glycosylase
Ligand
BDBM294522
Substrate
n/a
Meas. Tech.
Processive DNA synthesis assay
pH
7.5±n/a
EC50
7900±n/a nM
Comments
extracted
Citation
 Ricciardi, RPReitz, ABParker, MHBaugh, SDNuth, MGuan, H Antivirals against molluscum contagiosum virus US Patent  US10112895 Publication Date 10/30/2018 
Target
Name:
Uracil-DNA glycosylase
Synonyms:
OPG116 | UDG | UNG | UNG_VACCW
Type:
PROTEIN
Mol. Mass.:
25071.48
Organism:
Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strainWR))
Description:
ChEMBL_747132
Residue:
218
Sequence:
MNSVTVSHAPYTITYHDDWEPVMSQLVEFYNEVASWLLRDETSPIPDKFFIQLKQPLRNKRVCVCGIDPYPKDGTGVPFESPNFTKKSIKEIASSISRLTGVIDYKGYNLNIIDGVIPWNYYLSCKLGETKSHAIYWDKISKLLLQHITKHVSVLYCLGKTDYSNIRAKLESPVTTIVGYHPAARDRQFEKDRSFEIINVLLELDNKAPINWAQGFIY
  
Inhibitor
Name:
BDBM294522
Synonyms:
N-[(2-benzyloxyphenyl)methyl]- 1H-indazol-5-amine | US10112895, Compound 14
Type:
Small organic molecule
Emp. Form.:
C21H19N3O
Mol. Mass.:
329.3951
SMILES:
C(Nc1ccc2[nH]ncc2c1)c1ccccc1OCc1ccccc1
Structure:
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