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Target
Protein M2-1
Ligand
BDBM294945
Substrate
n/a
Meas. Tech.
Antiviral Assay
EC50
430±n/a nM
Citation
 Gomtsian, A; Dekhtyar, T; Frank, KE; Friedman, MM; Josephsohn, N; Molla, M; Vasudevan, A; Ng, IC; Chafeev, M Substituted cyanoguanidines as oral anti-virals US Patent  US10112911 Publication Date 10/30/2018 
Target
Name:
Protein M2-1
Synonyms:
Envelope-associated 22 kDa protein | M2-1 | M21_HRSVA | Matrix M2-1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22163.59
Organism:
Human respiratory syncytial virus A (strain A2)
Description:
P04545
Residue:
194
Sequence:
MSRRNPCKFEIRGHCLNGKRCHFSHNYFEWPPHALLVRQNFMLNRILKSMDKSIDTLSEISGAAELDRTEEYALGVVGVLESYIGSINNITKQSACVAMSKLLTELNSDDIKKLRDNEELNSPKIRVYNTVISYIESNRKNNKQTIHLLKRLPADVLKKTIKNTLDIHKSITINNPKESTVSDTNDHAKNNDTT
  
Inhibitor
Name:
BDBM294945
Synonyms:
US10112911, Example 1.10
Type:
Small organic molecule
Emp. Form.:
C24H27N7O
Mol. Mass.:
429.5175
SMILES:
CC(C)C1CN(CCN1\C(Nc1ccccc1C)=N/C#N)c1nc2ccccc2c(=O)[nH]1
Structure:
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