Reaction Details Report a problem with these data
Target
N-formyl peptide receptor 2
Ligand
BDBM350507
Substrate
n/a
Meas. Tech.
FLIPR
EC50
10000±n/a nM
Citation
 Viswanath, V; Beard, RL; Donello, JE; Hsia, E Use of agonists of formyl peptide receptor 2 for treating dermatological diseases US Patent  US10434112 Publication Date 10/8/2019 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM350507
Synonyms:
(2S)-2-({[(3,4- dichlorophenyl)amino]carbonyl}amino)- 3-phenylpropanoic acid | US10208071, Table 1.4 | US10434112, Table 1.4 | US10799518, Structure TABLE 1.4
Type:
Small organic molecule
Emp. Form.:
C16H14Cl2N2O3
Mol. Mass.:
353.2
SMILES:
OC(=O)C(Cc1ccccc1)NC(=O)Nc1ccc(Cl)c(Cl)c1
Structure:
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