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Target
N-formyl peptide receptor 2
Ligand
BDBM350509
Substrate
n/a
Meas. Tech.
FLIPR
EC50
1572±n/a nM
Citation
 Viswanath, V; Beard, RL; Donello, JE; Hsia, E Use of agonists of formyl peptide receptor 2 for treating dermatological diseases US Patent  US10434112 Publication Date 10/8/2019 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM350509
Synonyms:
3-phenyl-2-[({[4- (trifluoromethoxy)phenyl]amino} carbonyl)amino]propanoic acid | US10208071, Table 1.6 | US10434112, Table 1.6 | US10799518, Structure TABLE 1.6
Type:
Small organic molecule
Emp. Form.:
C17H15F3N2O4
Mol. Mass.:
368.3072
SMILES:
OC(=O)C(Cc1ccccc1)NC(=O)Nc1ccc(OC(F)(F)F)cc1
Structure:
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