Reaction Details Report a problem with these data
Target
Somatostatin receptor type 4
Ligand
BDBM276005
Substrate
n/a
Meas. Tech.
Camp Assay
EC50
9.30±n/a nM
Citation
 Mazzaferro, R; Ferrara, M; Giovannini, R; Lingard, I; Rudolf, K Morpholine and 1,4-oxazepane amides as somatostatin receptor subtype 4 (SSTR4) agonists US Patent  US10577336 Publication Date 3/3/2020 
Target
Name:
Somatostatin receptor type 4
Synonyms:
SOMATOSTATIN SST4 | SS-4-R | SS4-R | SS4R | SSR4_HUMAN | SST4R | SSTR4 | Somatostatin receptor type 4 (SSTR4)
Type:
Enzyme
Mol. Mass.:
42015.38
Organism:
Homo sapiens (Human)
Description:
P31391
Residue:
388
Sequence:
MSAPSTLPPGGEEGLGTAWPSAANASSAPAEAEEAVAGPGDARAAGMVAIQCIYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASSAALRHWPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLPIAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAIGLCYLLIVGKMRAVALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLLNLFVTSLDATVNHVSLILSYANSCANPILYGFLSDNFRRFFQRVLCLRCCLLEGAGGAEEEPLDYYATALKSKGGAGCMCPPLPCQQEALQPEPGRKRIPLTRTTTF
  
Inhibitor
Name:
BDBM276005
Synonyms:
US10071974, Example 116 | US10071974, Example 117 | US10071974, Example 118 | US10577336, Example 118
Type:
Small organic molecule
Emp. Form.:
C17H24N4O2
Mol. Mass.:
316.3981
SMILES:
Cc1cccn2c(ncc12)C(C)(C)NC(=O)C1CNCCOC1
Structure:
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