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Target
Mu-type opioid receptor
Ligand
BDBM432219
Substrate
n/a
Meas. Tech.
Human mu-Opioid Receptor Radioligand Assay
Ki
<100±n/a nM
Citation
 Goya, P; Torrens-Jover, A; Almansa-Rosales, C; Diaz-Fernández, J; Caamaño-Moure, A Arylamide derivatives having multimodal activity against pain US Patent  US10577360 Publication Date 3/3/2020 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM432219
Synonyms:
N-(1-Benzylpiperidin-4-yl)-N-[1-(3-fluoropyridin-4-yl)-1H-pyrazol-3-yl]thiophene-2- | US10577360, Example 82
Type:
Small organic molecule
Emp. Form.:
C25H24FN5OS
Mol. Mass.:
461.554
SMILES:
Fc1cnccc1-n1ccc(n1)N(C1CCN(Cc2ccccc2)CC1)C(=O)c1cccs1
Structure:
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