Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM434806
Substrate
n/a
Meas. Tech.
Binding Assays
Ki
1.15±0.18 nM
Citation
 Jacobson, KA; Tosh, DK; Salvemini, D A3 adenosine receptor agonists US Patent  US10577368 Publication Date 3/3/2020 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM434806
Synonyms:
US10577368, Compound 20
Type:
Small organic molecule
Emp. Form.:
C19H22N6O3
Mol. Mass.:
382.4164
SMILES:
CNC(=O)[C@]12CC1[C@H]([C@H](O)C2O)n1cnc2c(NC)nc(nc12)C#CC1CC1 |r|
Structure:
Search PDB for entries with ligand similarity: