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Target
Beta-2 adrenergic receptor
Ligand
BDBM50213119
Substrate
n/a
Meas. Tech.
Beta-2 AR binding assay
Ki
10466000±1461000 nM
Citation
 Wainer, IW; Bernier, M; Toll, LR; Jimenez, LA Use of fenoterol and fenoterol analogues in the treatment of glioblastomas and astrocytomas US Patent  US10617654 Publication Date 4/14/2020 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:
n/a
Mol. Mass.:
46461.69
Organism:
Homo sapiens (Human)
Description:
P07550
Residue:
413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM50213119
Synonyms:
(R)-(-)-5-(1-hydroxy-2-phenethylaminoethyl)-1,3-benzenediol | CHEMBL229620 | US10617654, Compound (R)-7 | US10925840, Compound (R)-7 | US9492405, (R)-7 | US9492405, 25
Type:
Small organic molecule
Emp. Form.:
C16H19NO3
Mol. Mass.:
273.327
SMILES:
O[C@@H](CNCCc1ccccc1)c1cc(O)cc(O)c1
Structure:
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