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Target
Kappa-type opioid receptor
Ligand
BDBM156453
Substrate
n/a
Meas. Tech.
enzyme assay
IC50
4.00±n/a nM
Citation
 Roberts, E; Guerrero, MA; Urbano, M; Rosen, H Kappa opioid ligands US Patent  US10118915 Publication Date 11/6/2018 
Target
Name:
Kappa-type opioid receptor
Synonyms:
K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42648.76
Organism:
Homo sapiens (Human)
Description:
P41145
Residue:
380
Sequence:
MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRVRNTVQDPAYLRDIDGMNKPV
  
Inhibitor
Name:
BDBM156453
Synonyms:
US10118915, Compound 247 | US9682966, 247
Type:
Small organic molecule
Emp. Form.:
C23H29N5O2
Mol. Mass.:
407.5087
SMILES:
Cc1noc(n1)-c1cc2cc(C)ccc2nc1N1CCC(CC1)NC1CCCOC1
Structure:
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