Reaction Details Report a problem with these data
Target
Retinaldehyde-binding protein 1
Ligand
BDBM323487
Substrate
n/a
Meas. Tech.
In Vitro Isomerase Inhibition Assay
IC50
55.0±n/a nM
Citation
 Scott, IL; Kuksa, VA; Orme, MW; Little, Jr., TL; Gall, A; Hong, F Alkoxy compounds for disease treatment US Patent  US10639286 Publication Date 5/5/2020 
Target
Name:
Retinaldehyde-binding protein 1
Synonyms:
CRALBP | Cellular retinaldehyde-binding protein | RLBP1 | RLBP1_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36462.25
Organism:
Homo sapiens (Human)
Description:
P12271
Residue:
317
Sequence:
MSEGVGTFRMVPEEEQELRAQLEQLTTKDHGPVFGPCSQLPRHTLQKAKDELNEREETREEAVRELQEMVQAQAASGEELAVAVAERVQEKDSGFFLRFIRARKFNVGRAYELLRGYVNFRLQYPELFDSLSPEAVRCTIEAGYPGVLSSRDKYGRVVMLFNIENWQSQEITFDEILQAYCFILEKLLENEETQINGFCIIENFKGFTMQQAASLRTSDLRKMVDMLQDSFPARFKAIHFIHQPWYFTTTYNVVKPFLKSKLLERVFVHGDDLSGFYQEIDENILPSDFGGTLPKYDGKAVAEQLFGPQAQAENTAF
  
Inhibitor
Name:
BDBM323487
Synonyms:
1-(3-(3-Amino-1-Hydroxypropyl)Phenoxy)Pentan-2-Ol | US10188615, Example 163 | US10639286, Example 163
Type:
Small organic molecule
Emp. Form.:
C14H23NO3
Mol. Mass.:
253.3373
SMILES:
CCCC(O)COc1cccc(c1)C(O)CCN
Structure:
Search PDB for entries with ligand similarity: