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Target
Retinaldehyde-binding protein 1
Ligand
BDBM323537
Substrate
n/a
Meas. Tech.
In Vitro Isomerase Inhibition Assay
IC50
550±n/a nM
Citation
 Scott, IL; Kuksa, VA; Orme, MW; Little, Jr., TL; Gall, A; Hong, F Alkoxy compounds for disease treatment US Patent  US10639286 Publication Date 5/5/2020 
Target
Name:
Retinaldehyde-binding protein 1
Synonyms:
CRALBP | Cellular retinaldehyde-binding protein | RLBP1 | RLBP1_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36462.25
Organism:
Homo sapiens (Human)
Description:
P12271
Residue:
317
Sequence:
MSEGVGTFRMVPEEEQELRAQLEQLTTKDHGPVFGPCSQLPRHTLQKAKDELNEREETREEAVRELQEMVQAQAASGEELAVAVAERVQEKDSGFFLRFIRARKFNVGRAYELLRGYVNFRLQYPELFDSLSPEAVRCTIEAGYPGVLSSRDKYGRVVMLFNIENWQSQEITFDEILQAYCFILEKLLENEETQINGFCIIENFKGFTMQQAASLRTSDLRKMVDMLQDSFPARFKAIHFIHQPWYFTTTYNVVKPFLKSKLLERVFVHGDDLSGFYQEIDENILPSDFGGTLPKYDGKAVAEQLFGPQAQAENTAF
  
Inhibitor
Name:
BDBM323537
Synonyms:
2-(3-(Cyclohexylmethoxy)Phenylsulfonyl)Ethanamine | US10188615, Example 125 | US10639286, Example 125
Type:
Small organic molecule
Emp. Form.:
C15H23NO3S
Mol. Mass.:
297.413
SMILES:
NCCS(=O)(=O)c1cccc(OCC2CCCCC2)c1
Structure:
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