Reaction Details Report a problem with these data
Target
Retinaldehyde-binding protein 1
Ligand
BDBM323442
Substrate
n/a
Meas. Tech.
In Vitro Isomerase Inhibition Assay
IC50
<100.0±n/a nM
Citation
 Scott, IL; Kuksa, VA; Orme, MW; Little, Jr., TL; Gall, A; Hong, F Alkoxy compounds for disease treatment US Patent  US10639286 Publication Date 5/5/2020 
Target
Name:
Retinaldehyde-binding protein 1
Synonyms:
CRALBP | Cellular retinaldehyde-binding protein | RLBP1 | RLBP1_BOVIN
Type:
Protein
Mol. Mass.:
36493.29
Organism:
Bovine
Description:
P10123
Residue:
317
Sequence:
MSEGAGTFRMVPEEEQELRAQLERLTTKDHGPVFGPCSQLPRHTLQKAKDELNEKEETREEAVRELQELVQAEAASGQELAVAVAERVQGKDSAFFLRFIRARKFHVGRAYELLRGYVNFRLQYPELFDSLSPEAVRCTVEAGYPGVLSTRDKYGRVVMLFNIENWDSEEITFDEILQAYCVILEKLLENEETQINGFCIIENFKGFTMQQAAGLRPSDLRKMVDMLQDSFPARFKAIHFIYQPWYFTTTYNVVKPFLKSKLLQRVFVHGEDLSSFYQEFDEDILPSDFGGTLPKYDGKAVAEQLFGPRDQTENTAF
  
Inhibitor
Name:
BDBM323442
Synonyms:
2-(3-(Cyclohexylmethoxy)Phenoxy)Ethanamine | US10188615, Example 7 | US10639286, Example 7
Type:
Small organic molecule
Emp. Form.:
C15H23NO2
Mol. Mass.:
249.3486
SMILES:
NCCOc1cccc(OCC2CCCCC2)c1
Structure:
Search PDB for entries with ligand similarity: