Reaction Details Report a problem with these data
Target
Retinaldehyde-binding protein 1
Ligand
BDBM323446
Substrate
n/a
Meas. Tech.
In Vitro Isomerase Inhibition Assay
IC50
<100.0±n/a nM
Citation
 Scott, IL; Kuksa, VA; Orme, MW; Little, Jr., TL; Gall, A; Hong, F Alkoxy compounds for disease treatment US Patent  US10639286 Publication Date 5/5/2020 
Target
Name:
Retinaldehyde-binding protein 1
Synonyms:
CRALBP | Cellular retinaldehyde-binding protein | RLBP1 | RLBP1_BOVIN
Type:
Protein
Mol. Mass.:
36493.29
Organism:
Bovine
Description:
P10123
Residue:
317
Sequence:
MSEGAGTFRMVPEEEQELRAQLERLTTKDHGPVFGPCSQLPRHTLQKAKDELNEKEETREEAVRELQELVQAEAASGQELAVAVAERVQGKDSAFFLRFIRARKFHVGRAYELLRGYVNFRLQYPELFDSLSPEAVRCTVEAGYPGVLSTRDKYGRVVMLFNIENWDSEEITFDEILQAYCVILEKLLENEETQINGFCIIENFKGFTMQQAAGLRPSDLRKMVDMLQDSFPARFKAIHFIYQPWYFTTTYNVVKPFLKSKLLQRVFVHGEDLSSFYQEFDEDILPSDFGGTLPKYDGKAVAEQLFGPRDQTENTAF
  
Inhibitor
Name:
BDBM323446
Synonyms:
1-((3-(3-Amino-1-Hydroxypropyl)Phenoxy)Methyl)Cyclohexanol | US10188615, Example 12 | US10639286, Example 12
Type:
Small organic molecule
Emp. Form.:
C16H25NO3
Mol. Mass.:
279.3746
SMILES:
NCCC(O)c1cccc(OCC2(O)CCCCC2)c1
Structure:
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