Target
Serine/threonine-protein kinase 17B
Ligand
BDBM441860
Substrate
n/a
Meas. Tech.
Activity Inhibition Assay
IC50
310±n/a nM
Citation
 Lee, KChoi, GLee, NRPark, SJJung, MEKim, SJYang, KLee, J Substituted pyrimidines for preventing or treating cancer and inflammatory diseases US Patent  US10647686 Publication Date 5/12/2020 
Target
Name:
Serine/threonine-protein kinase 17B
Synonyms:
DRAK2 | ST17B_HUMAN | STK17B | Serine/threonine-protein kinase 17B | Serine/threonine-protein kinase 17B (STK17B)
Type:
Enzyme
Mol. Mass.:
42332.49
Organism:
Homo sapiens (Human)
Description:
O94768
Residue:
372
Sequence:
MSRRRFDCRSISGLLTTTPQIPIKMENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYAAKFLKKRRRGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAGGEIFSLCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDFGMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSPFVGEDNQETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQQWDFENLFHPEETSSSSQTQDHSVRSSEDKTSKSSCNGTCGDREDKENIPEDSSMVSKRFRFDDSLPNPHELVSDLLC
  
Inhibitor
Name:
BDBM441860
Synonyms:
US10647686, Example (8)
Type:
Small organic molecule
Emp. Form.:
C13H14Cl3N5
Mol. Mass.:
346.643
SMILES:
NCCCNc1nc(Nc2ccc(Cl)c(Cl)c2)ncc1Cl
Structure:
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