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Target
Pulmonary surfactant-associated protein A1
Ligand
BDBM445759
Substrate
n/a
Meas. Tech.
Inhibition of fibrosis
IC50
140±n/a nM
Citation
Hood, J; Kumar KC, S; Wallace, DM; Mittapalli, GK; Hofilena, BJ; Mak, CC; Bollu, V; Eastman, B 5-substituted indazole-3-carboxamides and preparation and use thereof US Patent US10669240 Publication Date 6/2/2020
More Info.:
Target
Name:
Pulmonary surfactant-associated protein A1
Synonyms:
35 kDa pulmonary surfactant-associated protein | Alveolar proteinosis protein | COLEC4 | Collectin-4 | PSAP | PSP-A | PSPA | SFTA1_HUMAN | SFTP1 | SFTPA | SFTPA1 | SFTPA1B | SP-A | SP-A1
Type:
Protein
Mol. Mass.:
26234.12
Organism:
Human
Description:
Q8IWL2
Residue:
248
Sequence:
MWLCPLALNLILMAASGAVCEVKDVCVGSPGIPGTPGSHGLPGRDGRDGLKGDPGPPGPMGPPGEMPCPPGNDGLPGAPGIPGECGEKGEPGERGPPGLPAHLDEELQATLHDFRHQILQTRGALSLQGSIMTVGEKVFSSNGQSITFDAIQEACARAGGRIAVPRNPEENEAIASFVKKYNTYAYVGLTEGPSPGDFRYSDGTPVNYTNWYRGEPAGRGKEQCVEMYTDGQWNDRNCLYSRLTICEF