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Target
POU domain, class 2, transcription factor 2
Ligand
BDBM330052
Substrate
n/a
Meas. Tech.
Inhibition Assay
IC50
476±n/a nM
Citation
 Bacon, EM; Cai, ZR; Chen, X; Cottell, JJ; Desai, MC; Ji, M; Jin, H; Lazerwith, SE; Mish, MR; Morganelli, PA; Pyun, H; Taylor, JG; Trejo Martin, TA Substituted 3,4,5,6,8,10,14,14a-octahydro-2h-2,6-methanopyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazocines and methods for treating viral infections US Patent  US10689399 Publication Date 6/23/2020 
Target
Name:
POU domain, class 2, transcription factor 2
Synonyms:
Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2 | OCT2 | OCT2 | OTF-2 | OTF2 | Oct-2 | Octamer-binding protein 2 | Octamer-binding transcription factor 2 | Octamer-binding transcription factor 2 (OCT2) | PO2F2_HUMAN | POU domain, class 2, transcription factor 2 | POU2F2
Type:
PROTEIN
Mol. Mass.:
51217.88
Organism:
Homo sapiens (Human)
Description:
ChEMBL_109671
Residue:
479
Sequence:
MVHSSMGAPEIRMSKPLEAEKQGLDSPSEHTDTERNGPDTNHQNPQNKTSPFSVSPTGPSTKIKAEDPSGDSAPAAPLPPQPAQPHLPQAQLMLTGSQLAGDIQQLLQLQQLVLVPGHHLQPPAQFLLPQAQQSQPGLLPTPNLFQLPQQTQGALLTSQPRAGLPTQAVTRPTLPDPHLSHPQPPKCLEPPSHPEEPSDLEELEQFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAETMSVDSSLPSPNQLSSPSLGFDGLPGRRRKKRTSIETNVRFALEKSFLANQKPTSEEILLIAEQLHMEKEVIRVWFCNRRQKEKRINPCSAAPMLPSPGKPASYSPHMVTPQGGAGTLPLSQASSSLSTTVTTLSSAVGTLHPSRTAGGGGGGGGAAPPLNSIPSVTPPPPATTNSTNPSPQGSHSAIGLSGLNPSTGPGLWWNPAPYQP
  
Inhibitor
Name:
BDBM330052
Synonyms:
(1R,4S,12aS)-7-hydroxy-6,8-dioxo-N-(2,4,6-trifluorobenzyl)-1,2,3,4,6,8,12,12a-octahydro-1,4-methanodipyrido[1,2-a:1′,2′-d]pyrazine-9-carboxamide | US10689399, Compound 55 | US11548901, Compound 55 | US9663528, 55 | US9732092, Compound 55
Type:
Small organic molecule
Emp. Form.:
C21H18F3N3O4
Mol. Mass.:
433.3805
SMILES:
Oc1c2C(=O)N3[C@H]4CC[C@H](C4)[C@H]3Cn2cc(C(=O)NCc2c(F)cc(F)cc2F)c1=O |THB:12:11:7.8:10,3:5:7.8:10|
Structure:
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